love and hugs. I'll be vigilant, and hydrated... My crash comes in the third to fifth day after, and is unpredictable. It's important to take things day by day. Your doctor will talk to you about this treatment and its possible side effects before you agree to have treatment.TC comes from the name and initials of the drugs used. It was lovely to have my parents around for a couple of days, just to help look after me and my husband, and keep me company when he went off to work. The worst part for for me was self injecting neulasta after infusions. Organ and structural triggers of the urinary bladder such as Painful Bladder result in painful spasmodic contractions of the pelvic floor muscles and ligaments that mimic I have seen patients varying in age from teens to … Then, at the end of the cycle, the chemo schedule repeats to start the next cycle. I would definitely talk to Donna's doctor about the sleep issue. One well-known, common side effect of My worst days were always days 3-5. I thought I missed the bullet for several days after my first infusion too, but eventually, it was time to pay the piper. I continued to run and lift weights. This time they dropped my doses by 20% for both the Taxotere and Carboplatin. No Crash so far... 1 week in... can't wait for the next infusion (Tongue firmly planted in cheek) to see if my good fortune continues. Yes, for those who freak out at that number, my treatment is to a degree experimental, and is being supervised by the director of an NIH partner cancer center. So my sense of TASTE is returning... must be almost time for another dose... LOL. Take care. For me the fatigue was a bit cumulative. Also, please look upward to God because you need Him to replenish you and guide you....otherwise this will drain you. Like Donna, I too have a really good hubby, he took the reins of household chores together with my 17yr old daughter. Love Ronda. I stood up to brush my teeth and instantly felt better. I endured chemotherapy. Last reply: 6 years ago I got off lightly on the 4 AC, only had a couple of very bad days each cycle. I hope she's feels better, my prayers are with you and she during this time. Don't celebrate just yet. The worst part is my three-year-old asking me on a daily basis, “Mommy, are you sick today?” And me, without a good answer. Is day 4 the worst day? My first treatment it was a couple of days, then 1 more day, until it was a solid week. Do not use this information to diagnose or treat a health problem or disease without consulting with a qualified healthcare provider. The content on this site is for informational purposes only. Tell Donna, it will get better, food will taste good again, but in order to keep her strenght up she must eat even if she is not hungry or just taste awful. Just met w Onc. As she feels better, your wife will realize that she CAN do it. Fatal reactions have occurred in patients despite premedication, and all patients should be pretreated with corticosteroids, … Sleepless nights, yeah, very common and hard when you have to still get up to go to work. Neulasta shot .. threw me for a loop ... my acky body. I have finished 4 cycles so far with 4 more to go. NOTkidneystones said...JI find the mix of formats for peoples history a bit confusing, ... Post Edited (NOTkidneystones) : 7/18/2018 8:40:02 AM (GMT-6). If she knows that, then she could adjust her life that way for a while. I wish you two the very best. The prospect of 12 weekly taxol is a bit daunting. I have come to the conclusion, based on no medical foundation, that the crash is longer now (I am on session #17). This involves wearing a cold cap before, during and for one to two hours after your treatment with the chemotherapy drugs. We've heard that the Taxol is a lot easier. Hair lost started about. HI, My first does of chemo was not so bad. Taxol/Taxotere and Cytoxan (TC) therapy is one of the most common types of chemotherapy given to women with early-stage breast cancer. Lots of fatigue, sometimes diarrhea, sometimes a fever. I did not start feeling better until the 5 or 6th day after chemo. Taxotere is classified as a cytotoxic drug, which is a drug that stops rapidly dividing cells. Then yesterday; she was miserable all day; felt weak; and couldn't really describe the bad feeling in her body. so that I could totally veg out on Saturday and Sunday. Most don't understand the battle is not only physical, but mental, emotional, and spiritual. As the insomnia increased, so did my mood swings. Use of this online service is subject to the disclaimer and the terms and conditions. Yes....she is having a much more aggressive treatment plan than I did so I hope some other ladies here that have had that coctail and frequency will be able to give you more advice. – If you were diagnosed with breast cancer, then you clearly went through a physically and emotionally stressful time. Reversible marrow suppression was the major dose-limiting toxicity of TAXOTERE [see WARNINGS AND PRECAUTIONS].The median time to nadir was 7 days, while the median duration of severe neutropenia (<500 cells/mm 3) was 7 days.Among 2045 patients with solid tumors and normal baseline LFTs, severe neutropenia occurred in 75.4% and lasted for more than 7 days … The major dose-limiting toxicity of this drug is reversible marrow suppression. while I was on AC. I was on Taxotere and Cytoxan...day 3 and 4 were the worst for me. One of the chemo nurses (the nice one) did call her yesterday and say if she wasn't feeling better today to come in and they could give her some fluids, but I think she is gonna make it through without it. How many treatments is she having? As the treatments go on by the 4th one, it took me a few more extra days to get some energy. Good luck and take good care of her. Are you getting 4 or 6 Taxotere treatments? It Was The Best of Days, It Was The Worst of Days. My first infusion did not include Neulasta. (the 2%) And did you crash change your diet? I went to Moes, and got a Chicken Bowl (double beans, no rice, 1st meat in about, /www.healingwell.com/community/default.aspx?f=35&m=3987553&g=4010036#m4010036. Docetaxel (Taxotere) is a chemotherapy drug used to treat breast cancer. However she feels the 1st time is usually how she will feel for the remainder of that drug. Hair loss is usually gradual, but it can happen very quickly, possibly over a couple of days. and Friday, Donna did too much on Saturday, taking my daughter to the mall; shopping for most of the day. Taxotere’s Effect on Your Body. I did not get any worse for the remaining treatments. i think we all wish you and your wife nothing but good, and we can offer hope that you will make it through this, because you will get through this ; ), Susan is right everyone is different. I was on taxotere and id have my treatments on monday, and wednesday & thursdays were my bad days. Michele. The half-life of Taxotere is considered to be about 4 days (86 hours) before it drops to below 50% of the starting dose. The next drug will effect her differently. I would feel pretty good on Thursday and Friday and could have worked, but I used those days to do the errands I normally did on the weekends (grocery shopping, etc.) If you'd prefer, feel free to email me. Scalp cooling may stop you losing some or all of the hair on your head. Treatments started on Oct 2, 2014 and then every 21 days from there with the exception of late Dec. which was 25 days because the 21st day fell on Christmas day. Also don't hesitate to call the nurses and ask them if there is anything else you can do to help her to better tolerate these treatments. Remember that He is the source of your strength and that your help comes from Him. You are truly her hero and are to be applauded for that. I also went in every 2 weeks for 5 months. I never once became sick to the point of throwing up, etc. Of course, we each respond as individuals. I get steriods only the day of chemo and anti-nausea IV. I was on Taxotere and Cytoxan...day 3 and 4 were the worst for me. When I went through chemo, I was down for 1 week each time. No taste and hard to eat, yeap that too is very hard to manage. I felt sicker than a dog but it only lasted for 15 minutes and then it passed. Of those who experienced pain during the seven days after treatment, the average rating for pain at its worst was 5.15 for muscle pain and 5.02 for joint pain. I did however take 2 Ativan (Lorazepam) each night for week after the AC chemo just so I could sleep and take the edge off the feeling of anxiety. For ME - A/C was much easier than Taxol! After that, I have been okay - really tired and nothing tastes good so I am not eating well - but I learned from my first course of chemo that ended in April that I need to sleep when I am tired, so sometimes when I get home from work, I go right to sleep. Thurs. (factors are you size, weight, kidney function, metabolic rate and so on) That means 50% after first half life, 25% after second, 12.5 after third, 6.25 after fourth down to less than 2% after six. Intravenous route (Solution) Anaphylaxis and severe hypersensitivity reactions characterized by dyspnea and hypotension requiring treatment, angioedema, and generalized urticaria have occurred in clinical trials. Like many have stated, I was OK for the two days following and then felt like sh*t for two or three days and then was on the mend and better until the next treatment. Last night she was saying that she doesn't know how she is going to get through the next treatment, especially since they supposedly get worse each time. I'd have the chemo on Thursdays then by Sunday I was a mess and on Monday I was so sick and tired of it, that it SEEMED worse than it might have been. I had AC on Wed by that night I was having stomach issues. I started taking a iron supplement to support RBC..WBC is still okay. Since its initial approval by the U.S. Food and Drug Administration in 1996, it has gained additional approvals for treating cancers of the head, neck, stomach, and prostate, as well as non-small cell lung cancer. That was on the dose dense A/C. Days 1 & 7, I was tired but could function to some degree - I made it to infusions. The chemo does tend to keep you from sleeping sometimes even though you are very tired. So pretty much gone water or no after four days. Warning. However I do admit I did over the course of 4 AC treatments (3 weeks apart) felt almost depressed in the sense that I had little motivation to do anything, even getting out of bed, taking a shower, eating although I was hungary and going out in public became increasingly difficult for me. Please consult your healthcare provider with any questions or concerns you may have regarding your condition. After the week was up, I was almost my old self again. for me it was the week after the infusion.....I just fall apart....tired, ache, intestinal issues...etc. Taxol, so far has been significantly easier for me although it still has its side effects, some not too great but I feel more motivated and happier. I finished my initial session of chemo with four treatments of Taxotere. Charts like the one below show the damage an investor would have done if they missed out on just the best 25 days (out of 11,620) since 1970. My onocologist prefers it to Taxol. we can share our experiences, but that is what they are, OUR experiences. every Tuesday for 18 weeks straight .. Lorrie, You may want to ask the onc to prescribe her some ativan to take at night. For example, with some drugs, the chemo is given only on the first day of the cycle. Posted January 22, 2016 by Michael Batnick “Time in the market, not timing the market” is the rallying cry for buy and hold investors. Rough night last night; not sleeping well. Days 4 and 5 were the absolute worst - but to be honest, I didn't really take much in terms of painkillers. Last night about 9:00 the fog started lifting. When I was going through my cancer treatment one of the doctors in the treatment facility told me no two patients they were currently treating (100’s) were on the same drug regimen, and no two patients had the same reaction to any of the drugs. Her body is going through so much right now. Worst days when i was on 3chemo meds, taxotere, carbon, and Herceptin, were 3-5 days after. As you know from Carbo/Alimta, the effects of chemo can be cumulative so it's super important to stay hydrated, well nourished and exercise if you can. It is best to read this information with our general information about chemotherapy and the type of cancer you have.. Tell Donna to hang in there...and good luck to you Bob! The women most frequently described the pain as aching, tiring, nagging, exhausting, and tender. Well if I score this like a boxing match, so far I'm giving round one to Donna. Copyright 2000-2019 © Cancer Survivors Network, Ask for some ativan so she can sleep also, Hubby and Donna .. But when I received THP (Docetaxel/Taxotere) I didn´t get these injections, as in this combo there is less chemo (one chemo drug as opposed to three). You gals going through it try it and let me know. Thanks guys!! For example, when I received the FEC chemo I did have to get injections for five days (on days 8 to 12 after every cycle) to promote white cell formation (Filgrastim). Hematologic Reactions. I also drank an ensure every day the week of chemo...that does give you a boost. I am thankful to God that she has you as her supporter and encourager and a strength. 23 days: 10/7/2009: 1: stage II breast cancer: During treatments, body aches, chemo brain, neuropathy, chemically induced menopause were the worst ones. I know its early days as only had my 1st Taxotere on weds but I havent felt this well in AGES - no feeling sick - plenty of energy - good mood etc etc. I had no sleepless issues on A/C but on Taxol I did - first meds given me by my Chemo Dr did not help only gave horrible nightmares (which I don't normally have) but my PA switched me to the lowest does of another med and it worked great. Insomnia also made frequent visits during my chemo. Between the first and second treatment I bounced back pretty well, but between the 3rd and 4th it took longer. I keep thinking if I had made sure to eat something every hour maybe it wouldn't have been so bad. I am sorry that she is not feeling well. Please tell Donna to hang in there, and I wish the two of you .. all the best. And yes, for me at least, it is cumulative and is a bit worse each cycle. I went back to work on Tuesday, but wasn't feeling the greatest. Please tell her to take it easy and rest up a few days before her chemo and to plan on alot of down time for few days after the 2nd day after chemo. After first AC on Wed. and doing "okay" Thurs. Chemotherapy with Taxotere (docetaxel) might not be considered because the side effects are misunderstood. Worst Days On Taxotere Cramps Remedies Exercise some also deal with anxiety in the years leading up to full-blown menopause a time called perimenopause. By Monday I was OK to go back to work, just a little tired. Along with a predisone too..My "crash" comes on about, My 1st round I had 2 days extreme fatigue, 5 days of chemo. It's important to get as much rest as you can. Taxotere has been known to cause burning, tingling or numbness in your appendages due to nerve damage. Between blood pressure (3 a day), xanex (she's only taking at night), two kinds of anti-nausea drugs, claratin (supposed to help with bone pain after shot), a softener, and acidophilus. After taking the early lead she got knocked down and almost couldn't get off the mat. Six X sixteen is 96 hours or approximately four days. I don't know about AC, but when I was on TC, I was told that it's not cumulative, so I would not be feeling worse as chemo progressed. In fact, Taxol is the top-selling cancer drug worldwide. My last AC chemo was the easiest, the side effects were not that bad at all. Premedication with a corticosteroid pill starting a day prior to Taxotere infusion for 3 days is given to reduce the severity of fluid retention and allergic reactions. They did have "ice cubes", so I chewed those. Next time I will. She is also tired of taking pills. TC is used to treat breast cancer.It may sometimes be used to treat other cancers. Wishing you continued success with no crashes. Once the steroids wear off, usually by the 3rd day, you will see her get very fatigued and want to lay around the house most of the day. With others, it is given for a few days in a row, or once a week. Make sure she is getting alot of water, eat fruits and vegetables. If you have been diagnosed with breast cancer and are undergoing Taxotere (docetaxel) chemotherapy treatments, you are all too familiar with bad days. The 3rd week I just start to feel normal....and then whoops, time for another infusion to start the cycle. Hopefully, you might escape the crash but incase you don't, do make sure to take ISU-Cyclone's advice and if interested, see my diary of my chemo treatment here: Your body will tolerate that first dose without too much trouble..But as time goes on and the treatments start to add up, the effect will become more pronounced..I take a couple of Dexamethasone the day before, the day of and the day after the infusion to suppress any allergic reaction. On the eve of Oct 21 his temperature got to 101.3F in the evening so we went to the ER and they kept him in the hospital until they got his fever down and his white blood cells up. After Wednesday chemo; It was about 36 hours until she hit the wall; and then days 4 and 5 were the bottom. n Generally, chemotherapy is not as toxic as we think. Day 2 (Saturday) I still hadn't had much sleep (thank you steroids), and that metallic taste in my mouth was here to stay. No history of cancer in my family -- it's been waiting patiently for me! In October I finished 6 courses of docetaxel (Taxotere) , spread 3 weeks apart. Good luck with round two NOTkidneystones! Taxotere is used to treat breast cancer, non-small cell lung cancer, advanced stomach cancer, head and neck cancer as well as metastatic prostate cancer. I am on Taxotere and Cytoxin which I get every three weeks. Lots of fatigue, sometimes diarrhea, sometimes a fever. Cycles are most often 2 or 3 weeks long. Hypersensitivity I'm interested to hear how people have found taxotere - are the side effects better/worse/different to the AC? Docetaxel (Taxotere) is a chemotherapy drug used to treat breast cancer. I was 'tired' on days 3 & 4 on A/C but napping/resting helped. Taxotere (docetaxel anhydrous) is a chemotherapy drug commonly used to treat metastatic breast cancer. By Christina Morales | Apr 20, 2018. I did not get any worse for the remaining treatments. Days 3/4 to today, painful bones. My chemo cocktail was different than Donna's, but I did have infusions on Wednesdays (Cytoxan and Taxotere every 3 weeks - 4 treatments) with a Neulasta shot on Thursdays. But nothing ever happened and it passed as soon as it happened. xoxoxoxo Lynn. I was prescribed a steroid twice daily for 3 days following treatment. Good luck to Donna, I hope she gets the rest she needs. They can be debilitating. I haven't had a CRASH, but I've had a couple of days of SAGGING energy. some were bad and some were tolerable plus i also had insomnia because of the steriods. I'd also consider doing Wednesday infusions to put your worst days on the weekends (unless you work weekends). My bad days seemed to be the 3rd to 5th day after treatment .. and these days increased as my chemo treatments wore on. I was feeling like I was going to throw up, I felt like when you've drank way too much and you need to puke, but I sat on the edge of the bathtub, my husband brought a fan in and aimed it at me, I had a wet washcloth rubbed all over my face and for 15 minutes I thought I was gonna lose it. You are doing what God desires for you to do....just being there by her side in her support and being led by God as to what she needs and performing those things. Dear Bob, Lorrie. Your resistance to infection is usually at its lowest point around 7–14 days after the docetaxel has been given. (I have a new tagline for Taxotere: “Taxotere, putting the tax on your liver since 1996.”) When you are getting chemo, your liver can have an indirect effect on keeping your white blood cells, monocytes and neutrophils at a healthy level. It is also a blessing that you are reaching out to find information from others going through the same thing so that you can help your wife. It is administered intravenously through an IV. i had my first AC on June 10 (a Thursday), and the worst days for me were Sunday and Monday. `` ice cubes '', so far i 'm giving round one to two hours after your with... Hardly get out of it a lot easier the weekends ( unless you weekends... Some ativan so she can sleep also, hubby and Donna from Him 17yr old daughter is very hard eat! And 4 were the bottom teeth and instantly felt better the cycle, the chemo schedule repeats to start next. 4 days were you needed that third week to recover, she n't! 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