2010;14(32):1-206. JAMA 5-7-2008;299(17):2027-2036. Lancet 1999;354:353-4. Green TJ, Houghton LA, Donovan U, et al. View abstract. View abstract. Laitinen, M. H., Ngandu, T., Rovio, S., Helkala, E. L., Uusitalo, U., Viitanen, M., Nissinen, A., Tuomilehto, J., Soininen, H., and Kivipelto, M. Fat intake at midlife and risk of dementia and Alzheimer's disease: a population-based study. View abstract. Qin X, Li J, Spence JD, et al. Almeida, O. P., McCaul, K., Hankey, G. J., Norman, P., Jamrozik, K., and Flicker, L. Homocysteine and depression in later life. Deopa B, Parakh M, Dara P, et al. A., Eliasziw, M., Cattran, D. C., Churchill, D. N., Oliver, M. J., Fine, A., Dresser, G. K., and Spence, J. D. Effect of B-vitamin therapy on progression of diabetic nephropathy: a randomized controlled trial. Am J Clin Nutr 2005;82(3):636-643. Froster-Iskenius, U., Bodeker, K., Oepen, T., Matthes, R., Piper, U., and Schwinger, E. Folic acid treatment in males and females with fragile-(X)-syndrome. J Obstet Gynaecol. Zhu, S., Mason, J., Shi, Y., Hu, Y., Li, R., Wahg, M., Zhou, Y., Jin, G., Xie, Y., Wu, G., Xia, D., Qian, Z., Sohg, H., Zhang, L., Russell, R., and Xiao, S. The effect of folic acid on the development of stomach and other gastrointestinal cancers. Presented at the Annual Scientific Meeting Working Group/ Epidemiology and Prevention of the European Society of Cardiology; Venice, Italy. 11-15-2006;98(22):1607-1622. J Clin Periodontol 1980;7:402-14. Dierkes J, Domrose U, Ambrosch A, et al. 2016;57(6):725-728. A controlled trial of homocysteine lowering and cognitive performance. Christen WG, Glynn RJ, Chew EY, et al. Ford, A. H., Flicker, L., Thomas, J., Norman, P., Jamrozik, K., and Almeida, O. P. Vitamins B12, B6, and folic acid for onset of depressive symptoms in older men: results from a 2-year placebo-controlled randomized trial. Allen, L. H. and Peerson, J. M. Impact of multiple micronutrient versus iron-folic acid supplements on maternal anemia and micronutrient status in pregnancy. Bhutta, Z. 1988;30(1-2):377-392. View abstract. Corsi DJ, Gaudet LM, El-Chaar D, et al. View abstract. Medically reviewed by Sophia Entringer, PharmD. Southeast Asian J Trop.Med Public Health 1980;11(1):81-86. View abstract. View abstract. Effect of folic acid supplementation. Arterioscler.Thromb. Clin Chem. 2019 Oct;25(7):284-287. Interrelationship of rheumatoid arthritis, folic acid and aspirin. A., Kew, C., McKenney, J. L., Pacheco-Silva, A., Pesavento, T., Pirsch, J., Smith, S., Solomon, S., and Weir, M. Homocysteine-lowering and cardiovascular disease outcomes in kidney transplant recipients: primary results from the Folic Acid for Vascular Outcome Reduction in Transplantation trial. Luchsinger, J. Folate status of elderly women following moderate folate depletion responds only to a higher folate intake. J Natl.Cancer Inst. View abstract. Asfour, R., Wahbeh, N., Waslien, C. I., Guindi, S., and Darby, W. J. Folacin requirement of children. Folic acid is the synthetic version of the water-soluble vitamin folate, a B-vitamin (B9). View abstract. Malouf, R. and Grimley, Evans J. Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people. View abstract. Arch Neurol 2005;62:641-5. View abstract. Scand J Infect Dis Suppl 1986;49:17-30. Am.J Clin.Nutr 1982;35(4):710-714. Loria CM, Ingram DD, Feldman JJ, et al. J Clin Psychopharmacol 2003;23:309-13.. View abstract. View abstract. Int J Vitam.Nutr Res. Arch Intern Med 2001;161:695-700.. View abstract. Hematology: Basic Principles and Practice. Klingler, M., Blaschitz, A., Campoy, C., Cano, A., Molloy, A. M., Scott, J. M., Dohr, G., Demmelmair, H., Koletzko, B., and Desoye, G. The effect of docosahexaenoic acid and folic acid supplementation on placental apoptosis and proliferation. Pediatrics 1980;65(4):683-697. View abstract. View abstract. View abstract. Rev.Chil.Pediatr. View abstract. View abstract. Available at: https://www.bedfordlabs.com/BedfordLabsWeb/products/inserts/LCV-P02.pdf. We’ve separated out the dosing so it’s easier to understand. A., Smith, G. D., Talmud, P. J., van, Duijn C., Humphries, S. E., Price, J. F., Ebrahim, S., Lawlor, D. A., Hankey, G. J., Meschia, J. F., Sandhu, M. S., Hingorani, A. D., and Casas, J. P. Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-analysis of genetic studies and randomised trials. Kauwell GPA, Baily LB, Gregory JF, et al. Bull.World Health Organ 6-1-2011;89(6):402-411B. View abstract. J Inherit.Metab Dis. View abstract. Reducing stillbirths: behavioural and nutritional interventions before and during pregnancy. View abstract. View abstract. Arch.Dis.Child 1981;56(12):911-918. Tiemeier H, van Tuijl HR, Hofman A, et al. Van, Dam F. and Van Gool, W. A. Hyperhomocysteinemia and Alzheimer's disease: A systematic review. View abstract. J Pediatr 2004;144(4):500-504. The role of diet and nutrition in cervical carcinogenesis: a review of recent evidence. Obeid, R., Kasoha, M., Kirsch, S. H., Munz, W., and Herrmann, W. Concentrations of unmetabolized folic acid and primary folate forms in pregnant women at delivery and in umbilical cord blood. Can.J Public Health 2002;93(4):249-253. View abstract. Intestinal flora and endogenous vitamin synthesis. Rohan, T. E., Jain, M. G., Howe, G. R., and Miller, A. Eur J Clin Invest 2003;33(11):933-940. 2011;23(2):192-202. Eur J Vasc.Endovasc.Surg 2009;38(3):316-322. View abstract. View abstract. Fleming, A. F., Martin, J. D., Hahnel, R., and Westlake, A. J. Dietary folate and vitamin B12 intake and cognitive decline among community-dwelling older persons. (Accessed 18 March 10). View abstract. View abstract. Righetti, M., Serbelloni, P., Milani, S., and Ferrario, G. Homocysteine-lowering vitamin B treatment decreases cardiovascular events in hemodialysis patients. View abstract. Alter HJ, Zvaifler NJ, Rath CE. Hanrahan, P. S. and Russell, A. S. Concurrent use of folinic acid and methotrexate in rheumatoid arthritis. Jensen, O. N. and Olesen, O. V. Subnormal serum folate due to anticonvulsive therapy. Fisch GS, Cohen IL, Gross AC, et al. Tio M, Andrici J, Cox MR, Eslick GD. View abstract. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). View abstract. View abstract. Quiz: What Do You Know About Vitamin B12 Deficiency? N.Engl.J Med 2-14-2002;346(7):476-483. Am J Clin Nutr 2004;79(3):424-429. 1996;87(3-4):141-149. Cancer Epidemiol.Biomarkers Prev. View abstract. View abstract. Baumslag, N., Edelstein, T., and Metz, J. Eur J Clin Invest 1992;22(3):214-221. Srisupandit, S., Pootrakul, P., Areekul, S., Neungton, S., Mokkaves, J., Kiriwat, O., and Kanokpongsukdi, S. A prophylactic supplementation of iron and folate in pregnancy. View abstract. Calcif Tissue Int. Gann, P. H., Manson, J. E., Glynn, R. J., Buring, J. E., and Hennekens, C. H. Low-dose aspirin and incidence of colorectal tumors in a randomized trial. Perez, L., Heim, L., Sherzai, A., Jaceldo-Siegl, K., and Sherzai, A. Bostom AG, Shemin D, Gohh RY, et al. J Neurol.Neurosurg.Psychiatry 1991;54(12):1044-1054. Public Health Nutr 2008;11(8):807-821. Bronstrup A. Prediction of treatment response in geriatric depression from baseline folate level: interaction with an SSRI or a tricyclic antidepressant. View abstract. Int J Geriatr Psychiatry 2008;23(2):155-160. View abstract. Juhlin L, Olsson MJ. View abstract. Effects of folic acid treatment on homocysteine levels and vascular disease in hemodialysis patients. Kobrinsky NL, Ramsay NKC. Results of a 2-year vitamin B treatment on cognitive performance: secondary data from an RCT. J Perinat Med. View abstract. Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial. A., Ebbing, M., Bonaa, K. H., Nygard, O., Ueland, P. M., Grau, M. V., Baron, J. Br J Dermatol. View abstract. J Urol. Atherosclerosis 2012;222(2):307-313. View abstract. 1989;161(1):115-119. View abstract. View abstract. Homocysteine lowering effect of different multivitamin preparations in patients with end-stage renal disease. 1989;96(6):648-655. 2010;9(9):855-865. View abstract. BMC Med. Folic acid is a type of B vitamin that is normally found in foods such as dried beans, peas, lentils, oranges, whole-wheat products, liver, asparagus, beets, broccoli, brussels sprouts, and spinach. High amounts of homocysteine in the blood caused by the drug fenofibrate. Washington, DC: National Academy Press, 2000. 2010;91(6):1708-1715. 2013;30(4):593-9. Am.J.Clin Nutr. Psychother Psychosom 2003;72:80-7.. View abstract. Available at: https://books.nap.edu/books/0309065542/html/. View abstract. View abstract. View abstract. Butterworth CE, Hatch KD, Gore H, Mueller H, Krumdieck CL. Thompson, S. J., Torres, M. E., Stevenson, R. E., Dean, J. H., and Best, R. G. Periconceptional multivitamin folic acid use, dietary folate, total folate and risk of neural tube defects in South Carolina. View abstract. Lancet 2007;369:208-16. A procedure to open a blocked or narrowed blood vessel (angioplasty). 2011;6(2):e16473. Stroke. View abstract. Cochrane.Database.Syst.Rev 2006;3:CD004736. Am J Clin Nutr 1988;47:484-6. Where did you or where do you plan to purchase this product? Eur Heart J 1994;15(suppl):530. Potter, K., Hankey, G. J., Green, D. J., Eikelboom, J., Jamrozik, K., and Arnolda, L. F. The effect of long-term homocysteine-lowering on carotid intima-media thickness and flow-mediated vasodilation in stroke patients: a randomized controlled trial and meta-analysis. Baron, J. Bengt E. Gustafsson memorial lecture. Ann.Epidemiol. Isr.J.Med.Sci. 2012;98(1):151-158. 2. Lippmann SM, Klein EA, Goodman PJ, et al. Effect of the combination of uridine nucleotides, folic acid and vitamin B12 on the clinical expression of peripheral neuropathies. 2014 29;110(9):2327-38. If you’re planning to have a baby, it’s important that you take folic acid tablets for two to three months before … Folate therapy and in-stent restenosis after coronary stenting. Birth Defects Res A Clin Mol.Teratol. View abstract. Melse-Boonstra, A., Lievers, K. J., Blom, H. J., and Verhoef, P. Bioavailability of polyglutamyl folic acid relative to that of monoglutamyl folic acid in subjects with different genotypes of the glutamate carboxypeptidase II gene. J Natl Cancer Inst 1998;90:57-62. Dev.Pharmacol.Ther 1982;4 Suppl:58-65. 2006;11(2):133-139. Am Heart J 2006;151(2):282-287. Lumley, J., Watson, L., Watson, M., and Bower, C. Modelling the potential impact of population-wide periconceptional folate/multivitamin supplementation on multiple births. Arch Dermatol Res. View abstract. View abstract. JAMA 11-5-2008;300(17):2012-2021. Br Med J 2004;329:1375-6. 2020;6(1):00250-2019. 2012;45(16-17):1286-1294. Passeri M, Cucinotta D, Abate G, et al. Drugs and Aging 2000;16:251-60.. View abstract. 7-8-2002;181(1):65-71. Diet and premalignant lesions of the cervix: evidence of a protective role for folate, riboflavin, thiamin, and vitamin B12. Figueiredo, J. C., Mott, L. A., Giovannucci, E., Wu, K., Cole, B., Grainge, M. J., Logan, R. F., and Baron, J. A controlled study. View abstract. 2006;38(3-4):725-730. Folic acid and cyanocobalamin levels in serum and erythrocytes during low-dose methotrexate therapy of rheumatoid arthritis and psoriatic arthritis patients. Doshi, S. N., McDowell, I. F., Moat, S. J., Lang, D., Newcombe, R. G., Kredan, M. B., Lewis, M. J., and Goodfellow, J. Folate improves endothelial function in coronary artery disease: an effect mediated by reduction of intracellular superoxide? Feigelson, H. S., Jonas, C. R., Robertson, A. S., McCullough, M. L., Thun, M. J., and Calle, E. E. Alcohol, folate, methionine, and risk of incident breast cancer in the American Cancer Society Cancer Prevention Study II Nutrition Cohort. Wei Sheng Yan.Jiu. Kidney Int 2000;58:851-8. Stroke 2005;36(7):1581-1587. J Drugs Dermatol. View abstract. View abstract. Gandy, G. and Jacobson, W. Influence of folic acid on birthweight and growth of the erythroblastotic infant. Atherosclerosis 1999;147:317-26. 1973;30(2):165-169. Ophthalmic Epidemiol. Am.J.Clin Nutr. Ek, J., Behncke, L., Halvorsen, K. S., and Magnus, E. Plasma and red cell folate values and folate requirements in formula-fed premature infants. JAMA 6-23-2010;303(24):2486-2494. Taking folic acid might help slow kidney function decline in people with CKD. 2013;98(5):1272-81. View abstract. Probable benefits of increasing folic acid intakes. JAMA 2002;288:973-9. View abstract. Meta-analysis of folic acid efficacy trials in stroke prevention: Insight into effect modifiers. J.Natl.Cancer Inst. Ann.Rheum.Dis. Kinzie BJ, Taylor JW. Folic acid is the manufactured form of folate. View abstract. Hall, M. H. Folic acid deficiency and abruptio placentae. Drug interactions in intestinal transport of folic acid and methotrexate. Am J Hum Genet 2003;73. Ray, J. G., Vermeulen, M. J., Boss, S. C., and Cole, D. E. Declining rate of folate insufficiency among adults following increased folic acid food fortification in Canada. Am J Clin Nutr 1983;37(4):572-582. 2012;27(5):613-623. Arterioscler.Thromb.Vasc.Biol. Skorka, A., Gieruszczak-Bialek, D., Piescik, M., and Szajewska, H. Effects of prenatal and/or postnatal (maternal and/or child) folic acid supplementation on the mental performance of children. 2012;19(4):1292-1301. Br.J.Nutr. Cancer of the white blood cells (leukemia). View abstract. 2011;13(5-6):454-465. Gastroenterology 2008;134(1):29-38. Am J Clin Nutr 2009;90(6):1623-1631. View abstract. But it might reduce the risk of stroke in people with this condition. View abstract. Am.J Clin.Nutr 2005;81(5):1155-1162. 2003;12(2):161-164. Esfahani, A., Wong, J. M., Truan, J., Villa, C. R., Mirrahimi, A., Srichaikul, K., and Kendall, C. W. Health effects of mixed fruit and vegetable concentrates: a systematic review of the clinical interventions. View abstract. View abstract. 2008;8:24. View abstract. Ortiz Z, Shea B, Suarez-Almazor ME, et al. Ruscica M, Gomaraschi M, Mombelli G, Macchi C, Bosisio R, Pazzucconi F, Pavanello C, Calabresi L, Arnoldi A, Sirtori CR, Magni P. Nutraceutical approach to moderate cardiometabolic risk: results of a randomized, double-blind and crossover study with Armolipid Plus. Thorand, B., Kohlmeier, L., Simonsen, N., Croghan, C., and Thamm, M. Intake of fruits, vegetables, folic acid and related nutrients and risk of breast cancer in postmenopausal women. View abstract. View abstract. B., van der Beek, E. J., Orlebeke, J. F., and van den Berg, H. Vitamin B-6 supplementation in elderly men: effects on mood, memory, performance and mental effort. Women Health 1992;19:117-31. Am J Clin Nutr 1998;68:1104-10. Mol.Psychiatry 2006;11(4):352-360. Prostaglandins Leukot Essent Fatty Acids 1989;37(3):145-147. B. View abstract. View abstract. Multivitamin use and risk of prostate cancer in the National Institutes of Health-AARP Diet and Health Study. Bennett-Richards, K., Kattenhorn, M., Donald, A., Oakley, G., Varghese, Z., Rees, L., and Deanfield, J. E. Does oral folic acid lower total homocysteine levels and improve endothelial function in children with chronic renal failure? Soliman, E. Z. and Shalash, O. A. Colorectal adenomas in a randomized folate trial: the role of baseline dietary and circulating folate levels. View abstract. 6-1-1975;122(3):332-336. Guttormsen, A. Washington, DC: The American Academy of Pediatrics and the American College of Obstetricians and Gynecologists; 2012. Figueiredo JC, Grau MV, Haile RW, et al. View abstract. Folic acid supplementation for stroke prevention in patients with cardiovascular disease. Transplantation 4-27-2008;85(8):1146-1150. Int.Urol.Nephrol. Rosenblatt DS, Duschenes EA, Hellstrom FV, et al. Yang, H. T., Lee, M., Hong, K. S., Ovbiagele, B., and Saver, J. L. Efficacy of folic acid supplementation in cardiovascular disease prevention: an updated meta-analysis of randomized controlled trials. Cochrane.Database.Syst.Rev. View abstract. Effectiveness of folic acid supplementation in pregnancy on reducing the risk of small-for-gestational age neonates: a population study, systematic review and meta-analysis. View abstract. B., Ferrucci, L., Hardy, J., Worrall, B. View abstract. You should not use this medication if you have ever had an allergic reaction to folic acid. Effect of oral folic acid supplements on zinc, copper, and iron absorption and excretion. Neurol Res 2019;41(4):364-8. Gastroenterology. Am J Clin Nutr 2007;85:1586-91. A randomized comparison of routine versus selective iron supplementation during pregnancy. Effect of folic acid supplementation on the progression of carotid intima-media thickness: a meta-analysis of randomized controlled trials. View abstract. Araki, A., Sako, Y., Fukushima, Y., Matsumoto, M., Asada, T., and Kita, T. Plasma sulfhydryl-containing amino acids in patients with cerebral infarction and in hypertensive subjects. Burn, J., Bishop, D. T., Mecklin, J. P., Macrae, F., Moslein, G., Olschwang, S., Bisgaard, M. L., Ramesar, R., Eccles, D., Maher, E. R., Bertario, L., Jarvinen, H. J., Lindblom, A., Evans, D. G., Lubinski, J., Morrison, P. J., Ho, J. W., Vasen, H. F., Side, L., Thomas, H. J., Scott, R. J., Dunlop, M., Barker, G., Elliott, F., Jass, J. R., Fodde, R., Lynch, H. T., and Mathers, J. C. Effect of aspirin or resistant starch on colorectal neoplasia in the Lynch syndrome. Li Y, Huang T, Zheng Y, Muka T, Troup J, Hu FB. Klipstein FA, Berlinger FG, Reed LJ. Kidney Int. Herrmann, W. Significance of hyperhomocysteinemia. Ubbink, J. Paediatr.Perinat.Epidemiol. New Engl J Med 1981;305:1513-7. Vianna, A. C., Mocelin, A. J., Matsuo, T., Morais-Filho, D., Largura, A., Delfino, V. A., Soares, A. E., and Matni, A. M. Uremic hyperhomocysteinemia: a randomized trial of folate treatment for the prevention of cardiovascular events. This survey is being conducted by the WebMD marketing sciences department. View abstract. Lancet 7-31-1999;354(9176):407-413. Ann Epidemiol 2001;11:65-72.. View abstract. Int J Cancer. View abstract. Mao, G., Hong, X., Xing, H., Liu, P., Liu, H., Yu, Y., Zhang, S., Jiang, S., Wang, X., and Xu, X. Efficacy of folic acid and enalapril combined therapy on reduction of blood pressure and plasma glucose: a multicenter, randomized, double-blind, parallel-controlled, clinical trial. J Nutr 2001;131:1376S-1382S.. View abstract. Available at: https://www.ecfr.gov/cgi-bin/text-idx?SID=c7e427855f12554dbc292b4c8a7545a0&mc=true&node=pt21.2.101&rgn=div5#se21.2.101_179. View abstract. View abstract. Marcucci, R., Zanazzi, M., Bertoni, E., Rosati, A., Fedi, S., Lenti, M., Prisco, D., Castellani, S., Abbate, R., and Salvadori, M. Vitamin supplementation reduces the progression of atherosclerosis in hyperhomocysteinemic renal-transplant recipients. The natural history of vascular disease in homocystinuria and the effects of treatment. The effects of supplemental oral iron administration to pregnant women. View abstract. CONDITIONS OF USE AND IMPORTANT INFORMATION: View abstract. View abstract. Limited research found that taking folic acid during pregnancy does not reduce the risk of high blood pressure. Neurology 11-8-2005;65(9):1409-1414. 2014;8(1):61-8. Sydow, K., Schwedhelm, E., Arakawa, N., Bode-Boger, S. M., Tsikas, D., Hornig, B., Frolich, J. C., and Boger, R. H. ADMA and oxidative stress are responsible for endothelial dysfunction in hyperhomocyst(e)inemia: effects of L-arginine and B vitamins. View abstract. Combination of low-dose folic acid and pyridoxine for treatment of hyperhomocysteinaemia in patients with premature arterial disease and their relatives. View abstract. High dosage folic acid supplementation, oral cleft recurrence and fetal growth. Circulation 4-16-2002;105(15):1810-1815. 2009;17(1):13-21. Taking a specific nutritional supplement with added folic acid and possibly vitamin B12 does not seem to prevent diarrhea in children at risk of malnutrition. JAMA 8-20-2008;300(7):795-804. Most adults and children can take folic acid. Levi, F., Pasche, C., Lucchini, F., and La Vecchia, C. Dietary intake of selected micronutrients and breast-cancer risk. Li M, Li W, Gao Y, et al. Getting a scrip of folic acid is … Tonstad S, Silverstein M, Aksnes L, Ose L. Low dose colestipol in adolescents with familial hypercholesterolemia. Lowering blood homocysteine with folic acid based supplements: meta-analysis of randomized trials. 2009;85(4):269-273. Treatment of mild hyperhomocysteinemia in renal transplant recipients versus hemodialysis patients. BMJ 2009;338:b1673. 2003;12(10):980-986. JAMA. View abstract. Tabei SM, Mazloom M, Shahriari M, Zareifar S, Azimi A, Hadaegh A, Karimi M. Determining and surveying the role of carnitine and folic acid to decrease fatigue in ß-thalassemia minor subjects. 2003;9(4):I19-I24. View abstract. J Clin Rheumatol. View abstract. 2004;81(3):269-273. A. Cancer Epidemiol.Biomarkers Prev. Folate metabolism and anticonvulsant therapy. Am J Clin Nutr 2004;80(4):1024-1028. View abstract. Effects of 2-year vitamin B12 and folic acid supplementation in hyperhomocysteinemic elderly on arterial stiffness and cardiovascular outcomes within the B-PROOF trial. Asian Cardiovasc.Thorac.Ann. View abstract. Response of low birthweight infant to treatment with folic acid. Am J Clin Nutr 2010;92(6):1416-1422. View abstract. J Clin Lipidol. Baggott JE, Morgan SL, Ha T, et al. Food Nutr Bull 2009;30(4 Suppl):S533-S546. Decline in the prevalence of neural tube defects following folic acid fortification and its cost-benefit in South Africa. In case the body cannot produce adequate levels, this medicine is used to make up for the remaining … Surén P, Roth C, Bresnahan M, Haugen M, Hornig M, Hirtz D, Lie KK, Lipkin WI, Magnus P, Reichborn-Kjennerud T, Schjølberg S, Davey Smith G, Øyen AS, Susser E, Stoltenberg C. Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children. A simple treatment for a complex pathobiology. Can Med Assoc J 1976;115:217-23.. View abstract. Folic acid or vitamin B9 is a water-soluble synthetic folate. View abstract. Am.J Clin.Nutr 2006;84(2):361-370. Am.J.Clin Nutr. Folic acid and vitamin B-12 supplementation and common infections in 6-30-mo-old children in India: a randomized placebo-controlled trial. A randomized trial of aspirin to prevent colorectal adenomas. Pastore, A., De, Angelis S., Casciani, S., Ruggia, R., Di, Giovamberardino G., Noce, A., Splendiani, G., Cortese, C., Federici, G., and Dessi', M. Effects of folic acid before and after vitamin B12 on plasma homocysteine concentrations in hemodialysis patients with known MTHFR genotypes. Gastroenterology 1986;91:1476-82. Cancer Epidemiol. View abstract. J Nutr 2002;132(8 Suppl):2367S-2372S. Antioxidant vitamins or lactulose for the prevention of the recurrence of colorectal adenomas. van Dijk, R. A., Rauwerda, J. Omega-3 fatty acid treatment in 174 patients with mild to moderate Alzheimer disease: OmegAD study: a randomized double-blind trial. Incidence of cancer and mortality following alpha-tocopherol and beta-carotene supplementation: a postintervention follow-up. Br Med J 12-12-1970;4(5736):644-648. Am J Clin Nutr 1982;35:73-82. Non-cancerous growths in the large intestine and rectum (colorectal adenoma). Chest 1984;86:149-50. 2003;67(11):919-923. View abstract. Beaulieu AJ, Gohh RY, Han H, et al. MRC Vitamin Study Research Group. View abstract. Berg MJ, Fincham RW, Ebert BE, et al. Call your doctor for medical advice about side effects. Take ferrous sulfate and folic acid on an empty stomach, at least 1 hour before or 2 hours after a meal. Nature’s bounty is one of the reputed supplements brand that supplies 100% RDA of folic acid per each tablet. kidney disease (or if you are on dialysis). View abstract. Folic acid pills and most multivitamins sold in the United States have 100% of the daily value (DV) of folic acid; check the label to be sure. 2004;70(11):853-861. Holmes-Siedle M, Lindenbaum RH, and Galliard A. Vitamin supplementation and neural tube defects. Jenwitheesuk K, Surakunprapha P, Jenwitheesuk K, et al. View abstract. A. 2012;46(10):1349-1357. Calcium Polyp Prev Study Group. Obeid R, FinkGeisel U, Eckert R, and Herrmann W. Effect of the Bvitamins on cognitive function in elderly people with mild cognitive dysfunction. Effect of folic or folinic acid supplementation on the toxicity and efficacy of methotrexate in rheumatoid arthritis: a forty-eight week, multicenter, randomized, double-blind, placebo-controlled study. View abstract. Cardiovasc.Res 2003;57(1):244-252. 2006;76(10):714-717. Taking a daily prenatal vitamin — ideally starting three months before conception — can help ensure women get enough of this essential nutrient. Arch.Dis.Child 1974;49(9):736-738. Can Med Assoc J 1982;126:244-7. Am J Clin Nutr 1998;67:858-66. View abstract. 2012;250(7):1067-1074. View abstract. Roswall N, Olsen A, Christensen J, et al. View abstract. View abstract. Ravaglia, G., Forti, P., Maioli, F., Martelli, M., Servadei, L., Brunetti, N., Pantieri, G., and Mariani, E. Conversion of mild cognitive impairment to dementia: predictive role of mild cognitive impairment subtypes and vascular risk factors. View abstract. US Preventive Services Task Force, Bibbins-Domingo K, Grossman DC, et al. 2011;7(4):412-417. Houghton, L. A., Yang, J., and O'Connor, D. L. Unmetabolized folic acid and total folate concentrations in breast milk are unaffected by low-dose folate supplements. J Am Coll Cardiol 2003;41:2105-13. . Int Heart J. Folic acid for pregnancy is often recommended by many doctors to … A prospective study of plasma homocyst(e)ine and risk of ischemic stroke. Br J Cancer. Vitamin D and calcium supplementation reduces cancer risk: results of a randomized trial. Ann Pharmacother 1998;32:802-17. Arch.Gerontol.Geriatr. View abstract. Singh, J. Folate deficiency. Stroke 1990;21(4):572-576. View abstract. Kwok, T., Tang, C., Woo, J., Lai, W. K., Law, L. K., and Pang, C. P. Randomized trial of the effect of supplementation on the cognitive function of older people with subnormal cobalamin levels. 2009;85(4):295-302. The effects of folate supplementation on some coagulation parameter and oxidative status surrogates. View abstract. Olsen SF, Sorensen JD, Secher NJ, et al. J Clin Psychopharmacol 1987;7:201-2. Women of childbearing age, pregnant, and lactating women: 800 mcg orally, intramuscularly, subcutaneously or IV once a day. View abstract. 2013 Nov;30(8):742-7. MacLennan, R., Macrae, F., Bain, C., Battistutta, D., Chapuis, P., Gratten, H., Lambert, J., Newland, R. C., Ngu, M., Russell, A., and . B., Jr. Folic acid-based intervention in non-ST elevation acute coronary syndromes. Bowman, L., Armitage, J., Bulbulia, R., Parish, S., and Collins, R. Study of the effectiveness of additional reductions in cholesterol and homocysteine (SEARCH): characteristics of a randomized trial among 12064 myocardial infarction survivors. On iron, folate and vitamin B6 supplements in children taking phenytoin rohan, E.! Transport of folic acid in hemodialysis patients PA. intestinal malabsorption induced by paraminosalicylic acid ( letter.. A, Brouwer IA, van Wijngaarden JP, et al Ischaemic Heart disease among women 2.5-5 mg three weekly... Total homocysteine with folic acid protect against birth defects of the B vitamins in! P. micronutrients, birth weight gain in twin pregnancy B-vitamin status and on risk of ischemic stroke acid in... Vital before and … there are some important factors to consider before deciding on folic! And Ward, M. C., Evans DA, Bienias JL, Bury J, Goodwin folate! Is recommended that people with diabetes ( diabetic neuropathy ), Mason folic acid tablet, Jacques PF, al... 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